POS0997-HPR LUPUS MORTALITY IN RELATION TO THE OVERALL ENVIRONMENTAL QUALITY INDEX AND ITS FIVE DOMAINS

Background Growing evidence suggests a role of exposure to chemicals and industrial pollutants, such as hydrocarbons, silica, mercury, organochlorines trichloroethylene, particulate air pollution, UV radiation, infectious agents, living in certain geographic regions, sociodemographic factors increasing the risk and/or affecting outcome systemic lupus erythematosus (SLE). We utilized environmental quality index (EQI) developed by U.S. Environmental Protection Agency (EPA) represent better understand association between deaths. Five domains including air, water, land, built comprised EQI. Objectives Here, we summarize descriptive statistics exposures death compared them accidental deaths, heart disease malignant neoplasm. Methods The study population comprises all individual deaths from 2006 2011. describe mean/median EQI versus those who died other leading causes death, namely accident, disease, Cause-specific counts were obtained using ICD 10 codes: (M321, M328, M329), accident (V, W, X0-5, Y85-86), (I0, I11, I13, I2-4, I50-51), neoplasm (C0-8, C90-97). Results There 5,430 398,382 US total was significantly worse decedents than (p<0.001), but not when attributed Of five domains, built, three higher (p <0.05), (p<0.05) decedents. Conclusion Total well its suggesting possible contributing outcome. Further analysis is needed identify specific determinants, which are potentially modifiable improve REFERENCES: NIL. Acknowledgements: Disclosure Interests None Declared.